The 2011–2020 Trends of Data-Driven Approaches in Medical Informatics for Active Pharmacovigilance

Pharmacovigilance, the scientific discipline pertaining to drug safety, has been studied extensively and is progressing continuously. In this field, medical informatics techniques interpretation play important roles, appropriate approaches are required. study, we investigated analyzed trends of pharmacovigilance systems, especially data collection, detection, assessment, monitoring processes. We used PubMed collect papers on published over past 10 years, a total 40 significant determine characteristics databases analysis methods identify safety indicators. Through systematic reviews, identified difficulty standardizing terminology establishing an adverse reactions (ADR) evaluation system in pharmacovigilance, their corresponding implications. found that guidelines for active using big still required should continue be developed.